研究人员

唐越

唐越

唐越

博士后

+86(10)64806118
tangy@im.ac.cn
北京市朝阳区北辰西路1号院3号

研究方向

庚糖类免疫激活剂的分布与新分子发现

教育经历

  • 2017.9-2021.6 中国科学院微生物研究所 博士
  • 2014.9-2017.6 齐鲁工业大学 硕士(中国科学院微生物所客座硕士)
  • 2010.9-2014.7 齐鲁工业大学 学士

工作经历

  • 2022-至今 中国科学院微生物研究所,研究人员

获奖及荣誉

  • 微生物研究所2024年度特别研究助理"微苗计划"一等奖

基金项目

  • 2025国家自然科学基金青年科学基金C类
代表性论文

The β-d-manno-heptoses are immune agonists across kingdoms

Tang Yue; Tian, Xiaoying; Wang, Min; Cui, Yinglu; She, Yang; Shi, Zhaoxiang; Liu, Jiaqi; Mao, Huijin; Liu, Lilu; Li, Chao; Zhang, Yuwei; Li, Pengwei; Ma, Yue; Sun, Jinyuan; Du, Qing; Li, Jie; Wang, Jun; Li, De-feng; Wu, Bian; Shao, Feng; Chen, Yihua

Science 2024
研究动态
2024年10月8日

Research Highlight | Discovery of biosynthetic enzymes for β-D-manno-heptoses across kingdoms: novel agonists for ALPK1/NF-κB-dependent immune response

A recent study by Tang et al. in Science reveals the cross-kingdom widespread occurrence of functional NDP-heptose biosynthetic enzymes (HBEs) that accounts for the synthesis of NDP-heptoses to activate the ALPK1-dependent innate immune response.

阅读更多

近年代表性研究论文

(#共同第一,*通讯作者)

NDP-β-d-manno-heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms

Tang Yue; Zhong, Zijian; Mao, Huijin; Chen, Yihua

Clinical and Translational Medicine 2024 Research Article DOI: 10.1002/ctm2.70103

The β-d-manno-heptoses are immune agonists across kingdoms

Tang Yue; Tian, Xiaoying; Wang, Min; Cui, Yinglu; She, Yang; Shi, Zhaoxiang; Liu, Jiaqi; Mao, Huijin; Liu, Lilu; Li, Chao; Zhang, Yuwei; Li, Pengwei; Ma, Yue; Sun, Jinyuan; Du, Qing; Li, Jie; Wang, Jun; Li, De-feng; Wu, Bian; Shao, Feng; Chen, Yihua

Science 2024 Research Article DOI: 10.1126/science.adk7314

Engineering the C3N Pathway as a Short Detour for De Novo NAD+ Biosynthesis in Saccharomyces cerevisiae

Li Xinli, Tang Yue, Ding Yong, Li Pengwei & Chen Yihua

Fermentation 2023 Research Article DOI: 10.3390/fermentation9100886

Construction and heterologous expression of the di-AFN A(1) biosynthetic gene cluster in Streptomyces model strains

Yihua Wei Weijia; Wang Wenzhao; Li Chao; Tang Yue; Guo Zhengyan; Chen

Chin J Nat Med 2022 Research Article DOI: 10.1016/S1875-5364(22)60197-3

A conservative distribution of tridomain NDP-heptose synthetases in actinobacteria

Tang Yue, Tang Wei, Wang Min, Zhang Zhilong & Chen Yihua

Science China-Life Sciences 2022 Research Article DOI: 10.1007/s11427-021-2000-2

Heptose-containing bacterial natural products: structures, bioactivities, and biosyntheses

Guo Zhengyan, Tang Yue, Tang Wei & Chen Yihua

Natural Product Reports 2021 Research Article DOI: 10.1039/d0np00075b

Deciphering the Biosynthesis of TDP-beta-L-oleandrose in Avermectin

Tang Yue, Wang Min, Qin Hua, An Xiangxiang, Guo Zhengyan, Zhu Guoliang, Zhang Lixin & Chen Yihua

Journal of Natural Products 2020 Research Article DOI: 10.1021/acs.jnatprod.0c00902